Pratap Challa, M.D.

Assistant Professor of Ophthalmology

Department:
Ophthalmology

Division:
Glaucoma

Email:
chall001mcdukeedu

Mailing Address:
DUMC 3802
Durham, NC 27710

Telephone:
919-684-3283

Training:
M.D., University of Florida School of Medicine

Last Updated:
December 28, 2001

Clinical Interests:
Diagnosis and treatment of glaucoma including medical, laser, and surgicaltherapies, cataract evaluation and treatment, glaucoma implant surgery, andcombined glaucoma and cataract surgery, research interests include geneticstudies of inherited eye diseases and novel drug delivery techniques

Research Interests:
Since joining the faculty on July 1, 2000 I have enjoyed a rapidly enlarging clinical practice, which includes medical and surgical glaucoma management as well as evaluation of comprehensive ophthalmology patients. I have also continued several research projects that were begun during the previous year and submitted a K23 grant application entitled "The molecular basis of pseudoexfoliation syndrome." This grant should provide salary support and protected research time to allow me to develop into an independent investigator. Other active research projects include ocular drug delivery using long term drug implants, testing novel candidate drugs, and several clinical research projects. Regarding my didactic interests, I have been promoted to the position of residency director this year. My goals for the residency program are to provide the best learning environment for our trainees and provide them the tools to develop into the leaders of the future. I actively support their participation in and encourage them to formulate their own research projects. I am currently mentoring the following residents in their respective research projects: Jerry Hu, MD, Herb Greenman, MD, Dianna Miele, MD, and Jennifer Weizer, MD.

Publications:
2001 -- Allingham, R.R., Seo B., Bembe M, Rampersaud E., Challa P., Parish, T., Gilbert J., Pericak-Vance M.A., Klintworth G.K., Vance J.M. A small duplication of the terminal region of chromosome 4p35 is associated with hereditary benign intrepithelial dyskeratosis, Am J Hum Genet. 2001 Feb; 68(2): 491-4.

1999 -- Fanous M.M., Challa P., Maren T.H. Comparison of intraocular pressure lowering by topical and systemic carbonic anhydrase inhibitors in the rabbit. Ocul Pharmacol Ther. 1999 Feb; 15 (1): 51-7.

-- Rahul N. Khurana 1, MS, Paul P. Lee 123, MD, JD, Pratap Challa1, MD. Readability of Ocular Medication Inserts. Ophthalmology Submitted

-- Pratap Challa, Kevin D. O'Neal, Leon W. Herndon, Terry A. Cox, Nauman R. Imami, MD and Paul P. Lee who Attends Community Eye Screenings? A Survey of Participants. Arch Ophthalmol Submitted

-- P. Challa, MD, L.W. Herndon, MD, M.A. Hauser, PhD, B.W. Broomer, CCRP, M.A. Pericak-Vance, PhD, R.R. Allingham, MD, Incidence of Myocilin Mutations in Individuals with POAG From West Africa. J. Glaucoma submitted