John Andrew Crump, M.B.B.Ch.

Associate Professor of Medicine

Department:
Medicine

Division:
Infectious Diseases

Email:
crump017mcdukeedu

Mailing Address:
Box 102359, DUMC
Durham, NC 27710

Telephone:
919-684-2660

Training:
M.B.B.Ch., University of Otago

Last Updated:
October 13, 2009

Clinical Interests:
Clinical infectious diseases, clinical microbiology, and epidemiology,particularly as practiced in resource-constrained countries

Research Interests:
I am based in northern Tanzania where I am Site Leader for Duke University’s collaborative research program based at Kilimanjaro Christian Medical Centre and Director of Tanzania Operations for the Duke Global Health Institute. I oversee the design and implementation of research studies on infectious diseases, particularly febrile illness, invasive bacterial disease, HIV-associated opportunistic infections, clinical trials of antiretroviral therapy and prevention of mother-to-child transmission of HIV, and infectious diseases diagnostics. In addition, I am a medical epidemiologist with the US Centers for Disease Control and Prevention (CDC). My CDC work focuses on enteric infection epidemiology and prevention in developing countries, particularly invasive salmonelloses.

Publications:
2009 -- Pubmed # 19591599 -- Morpeth SC, Ramadhani HO, Crump JA. Invasive non-Typhi Salmonella disease in Africa. Clin Infect Dis. 2009 Aug 15;49(4):606-11.

2008 -- Pubmed # 18285712 -- Morpeth SC, Thielman NM, Ramadhani HO, Hamilton JD, Ostermann J, Kisenge PR, Shao HJ, Reller LB, Itemba DK, Sam NE, Bartlett JA, Shao JF, Crump JA. Effect of trimethoprim-sulfamethoxazole prophylaxis on antimicrobial resistance of fecal Escherichia coli in HIV-infected patients in Tanzania. J Acquir Immune Defic Syndr. 2008 Apr 15;47(5):585-91.

2008 -- Pubmed # 18812538 -- Crump JA, Sugarman J. Ethical considerations for short-term experiences by trainees in global health. JAMA. 2008 Sep 24;300(12):1456-8.

2008 -- Pubmed # 18212096 -- Crump JA, Kretsinger K, Gay K, Hoekstra RM, Vugia DJ, Hurd S, Segler SD, Megginson M, Luedeman LJ, Shiferaw B, Hanna SS, Joyce KW, Mintz ED, Angulo FJ, . Clinical response and outcome of infection with Salmonella enterica serotype Typhi with decreased susceptibility to fluoroquinolones: a United States foodnet multicenter retrospective cohort study. Antimicrob Agents Chemother. 2008 Apr;52(4):1278-84.

2007 -- Pubmed # 17990233 -- Ramadhani HO, Thielman NM, Landman KZ, Ndosi EM, Gao F, Kirchherr JL, Shah R, Shao HJ, Morpeth SC, McNeill JD, Shao JF, Bartlett JA, Crump JA. Predictors of incomplete adherence, virologic failure, and antiviral drug resistance among HIV-infected adults receiving antiretroviral therapy in Tanzania. Clin Infect Dis. 2007 Dec 1;45(11):1492-8.

2006 -- Pubmed # 16317205 -- Thielman NM, Chu HY, Ostermann J, Itemba DK, Mgonja A, Mtweve S, Bartlett JA, Shao JF, Crump JA. Cost-Effectiveness of Free HIV Voluntary Counseling and Testing Through a Community-Based AIDS Service Organization in Northern Tanzania. Am J Public Health. 2006 Jan;96(1):114-9.

2005 -- Pubmed # 16046440 -- Crump JA, Otieno PO, Slutsker L, Keswick BH, Rosen DH, Hoekstra RM, Vulule JM, Luby SP. Household based treatment of drinking water with flocculant-disinfectant for preventing diarrhoea in areas with turbid source water in rural western Kenya: cluster randomised controlled trial. BMJ. 2005 Sep 3;331(7515):478.

2004 -- Pubmed # 15298225 -- Crump JA, Luby SP, Mintz ED. The global burden of typhoid fever. Bull World Health Organ. 2004 May;82(5):346-53.

2003 -- Pubmed # 14523767 -- Crump JA, Reller LB. Two decades of disseminated tuberculosis at a university medical center: the expanding role of mycobacterial blood culture. Clin Infect Dis. 2003 Oct 15;37(8):1037-43.