Molecular Medicine (MolMed)

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Study Program Director: David Hsu, M.D., Ph.D.

This interdepartmental study program is designed to provide third year medical students with an in-depth basic science or translational research experience in oncological sciences, regenerative medicine, the nutritional and metabolic mechanisms of chronic disease or the molecular basis of disease. Faculty members in this study track come from numerous departments, including Medicine, Biochemistry, Cell Biology, Immunology, Pathology, and Pharmacology and Cancer Biology. Students who elect this study program undertake a research project in a laboratory under the guidance of a faculty preceptor and participate in appropriate seminar series. In addition, with the permission of their mentor and study program director, students may take course work each term to complement their research interests. Due to the wide range of research opportunities available, course work is individually tailored to the interests of the student by the faculty preceptor. There are four (4) discreet sub tracks to accommodate the diversity of interest in Molecular Medicine.

Oncological Sciences Track: Co-Director, Cory Adamson, M.D., MHSc, MPH
This interdepartmental study program is designed to provide third year medical students with an in-depth basic science or translational research experience in oncological science. Faculty in the study program are engaged in investigating oncogenes, tumor suppressor genes, growth factors, chromosomal abnormalities, cellular invasion and metastases, proliferation, differentiation, apoptosis, tumor hypoxia, tumor angiogenesis, chemical/radiation/viral carcinogenesis, biologic and immunotherapy principles, radiobiology and hyperthermic oncology, and the pharmacology of cancer chemotherapy. The program is directed at students potentially interested in a career in oncology and cancer research. Faculty members in this study track come from numerous departments, including Medicine, Biochemistry, Cell Biology, Immunology, Pathology, and Pharmacology and Cancer Biology. Students who elect this study program undertake a research project in a laboratory under the guidance of a faculty preceptor and participate in appropriate seminar series. In addition, with the permission of their mentor and study program director, students may take course work each term to complement their research interests. Due to the wide range of research opportunities available, course work is individually tailored to the interests of the student by the faculty preceptor.

Regenerative Medicine Track
This interdepartmental study program is designed to provide third year medical students with an in-depth basic science or translational research experience in the fields of developmental and stem cell biology. Faculty in the study program are engaged in investigating mechanisms of embryonic development, developmental genetics, stem cells in various tissues from both humans and model organisms, the factors that regulate the balance between stem cell self-renewal and differentiation, the stem cell niche, the role of cancer stem cells in human cancer and the use of stem cells for therapy. The program is directed at students potentially interested in a career in regenerative medicine. Faculty members in this study track come from numerous departments, including Medicine, Biochemistry, Cell Biology, Pediatric, Pharmacology and Cancer Biology and Radiation Oncology. Students who elect this study program undertake a research project in a laboratory under the guidance of a faculty preceptor and participate in appropriate seminar series. In addition, with the permission of their mentor and study program director, students may take course work each term to complement their research interests. Due to the wide range of research opportunities available, course work is individually tailored to the interests of the student by the faculty preceptor.

Molecular Basis of Disease Study Track
This interdepartmental study program is designed to provide third year medical students with an in-depth basic science or translational research experience in defining molecular mechanisms that underlie biological processes, using an integrated approach that combines chemistry, enzymology, biophysics, structural biology, computational biology, cell biology and genetics. Faculty members in this study track come from numerous departments, including Biochemistry, Cell Biology, Medicine, Microbiology and Medical Genetics, Pathology, and Pharmacology and Cancer Biology. Students who elect this study program undertake a research project in a laboratory under the guidance of a faculty preceptor and participate in appropriate seminar series. In addition, with the permission of their mentor and study program director, students may take course work each term to complement their research interests. Due to the wide range of research opportunities available, course work is individually tailored to the interests of the student by the faculty preceptor.

Nutritional and Metabolic Mechanisms of Chronic Disease Study Track
This interdepartmental study program is designed to provide third year medical students with an in-depth basic science or translational research experience in nutritional and metabolic mechanisms involved in the pathogenesis of chronic diseases.  Faculty in the study program are engaged in investigating fundamental nutritional and metabolic regulatory mechanisms, including application of comprehensive metabolic analysis tools ("metabolomics") for the diagnosis and treatment of individuals with chronic diseases. Faculty members in this study track come from numerous departments, including Biochemistry, Cell Biology, Medicine, Microbiology and Medical Genetics, Pathology, and Pharmacology and Cancer Biology. Students who elect this study program undertake a research project in a laboratory under the guidance of a faculty preceptor and participate in appropriate seminar series. In addition, with the permission of their mentor and study program director, students may take course work each term to complement their research interests. Due to the wide range of research opportunities available, course work is individually tailored to the interests of the student by the faculty preceptor.

 

Translational Pharmacology Track: Study Program Co-Directors, J. Victor Nadler, Ph.D. Robert Noveck, M.D., Ph.D.
This interdepartmental study program is designed to provide third year medical students with an in-depth translational research experience in drug development and early-stage clinical drug testing.  Faculty in the study program either are or have been engaged in preclinical drug development or in Phase I/IIA clinical testing.  The program is directed at students potentially interested in making drug development a component of their future career.  Faculty members in this study track come from numerous departments, including Pharmacology and Cancer Biology, Neurobiology, Medicine, Pediatrics, Radiation Oncology, Anesthesiology, Radiology, Surgery, and Biomedical Engineering.  Students who elect this study program either undertake a research project in a laboratory under the guidance of a faculty preceptor or design and execute a component of a Phase I/IIA clinical trial.  Students are expected to view the Principles of Clinical Pharmacology course offered online by the NIH Clinical Center and to participate in presentations and discussions of issues discussed in this course as their time permits.  In addition, with the permission of their mentor and study program director, students may take course work each term to complement their research interests.  Due to the wide range of research opportunities available, course work is individually tailored to the interests of the student by the faculty preceptor.